Justice League of America #222 (DC, 1984 — Cover A)

The Justice League conducts an interview with the refugee animal woman, Reena. Reena tells them how she was once the assistant and lover of Rex Rogan, CEO of Repli-Tech Industries. When the company went bankrupt, Rogan and the board members (as well as Reena) volunteered to gain newfound power by way of a scientific process that manipulated their DNA, transforming them into animals. Calling himself Maximus Rex, Rogan established a gladiatorial combat arena, in which he and the other Ani-Men participated in vicious combat sports for the benefit of wealthy patrons. Reena can no longer bear the guilt of having associated with such a monstrous process and now turns to the JLA for help.